New Frontiers in Medicine

Therapies reimagined at the root cause of disease, not consequence.

HAYA’s Regulatory Genome Engine Input
HAYA’s Regulatory Genome Engine Output

Driven by the Regulatory Genome

While most medicines target proteins, the true control system of the disease causality and cell’s regulatory networks lies within the 98% of the genome that doesn’t code for proteins.

This is the regulatory genome: the instruction layer that governs cell identity, behavior, and fate.

HAYA’s Regulatory Genome Engine

Building the Most Comprehensive Atlas to Decode Disease and Reprogram Cell States

A causally-informative atlas of the regulatory genome to transform how complex diseases are understood and treated

We generate deep, multimodal biological insight.

Through high-resolution functional genomics integrating transcriptomics, epigenomics, chromatin accessibility, and long-read sequencing, we uncover the regulatory logic that governs pathological cell states leveraging disease-relevant models and patient data from the start.

We integrate proprietary causal intelligence.

Our platform combines deep biology with a stack of advanced computational algorithms to power the HAYAtlasTM. This unified, scalable engine links non-coding RNAs to complex disease causality and predicts their potential to reprogram cell fate, enabling us to nominate mechanistically grounded targets with unprecedented speed and precision.

This is where data becomes knowledge

Causal Insight. Predictive Power. RNA Medicines with Impact.

HAYAtlasTM enables the identification of causal RNA-guided targets, design of programmable RNA-medicines, and translation through integrated biomarker discovery. By mapping the regulatory genome with causal clarity, we unlock and accelerate new class of RNA-guided therapies that act on the molecular origin of complex disease to restore health.

Where causal biology…

…becomes medicine

Key Stats

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HAYA Engine by the Numbers

New IncRNAs* ID
3080%
Compared to GENCODE per Cell-State
New IncRNAs*
300'000
Average Novel lncRNA Transcripts
Collaboration
1
Novel Targets ID for Obesity
Regulatory Genome Atlases & Development Programs
3
Cardiac, Pulmonary and Oncology

*lncRNAs, long non-coding RNAs


What Makes Us Different

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The HAYA Advantage

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Causal Precision

We target regulatory RNAs that drive disease at the cell-state level, maximizing tissue specificity and therapeutic impact.

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Execution Speed

The predictive power of our integrated platform significantly compresses drug development timelines. Our goal is to go from target discovery to early clinical within 3-years.

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Scalable Versatility

Our platform enables repeatable drug discovery across fibrotic, metabolic, and age-related diseases.

Science Guides Us.
The Genome Powers Us.
Patients Ground Us.