Dr. Miller is a cardiologist and cardiovascular researcher in the UK. He leads a heart failure with preserved ejection fraction clinical service and is the director of a cardiovascular magnetic resonance research center. Dr Miller conducts experimental medicine trials evaluating the efficacy and mechanism of new and repurposed therapies designed to target key cardiovascular disease processes. He develops quantitative imaging biomarkers of cardiovascular injury and adaptation and applies these biomarkers to deeply phenotype cardiovascular health and disease.
He also employs the imaging biomarkers in the experimental medicine trials for predictive enrichment, and to measure the effect of therapies, and as such, he uses imaging to connect human cardiovascular biology with drug mechanisms of action in order to increase the likelihood of Phase III success.